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single-cell secretome human inflammation panel  (Bruker Corporation)


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    Bruker Corporation single-cell secretome human inflammation panel
    IL-23 enhances production of cytotoxic molecules and IL-10 by MAIT cells (A) Percentage of IL-23R positive cells in different immune cell populations was assessed by flow cytometry on freshly isolated PBMCs ( n = 11). (B and C) PBMC were activated with Tet for 6 days or left unstimulated (black). Sorted MAIT cells (CD3 + CD161 + Va7.2 + ) were re-stimulated with Tet in the absence (gray) or presence of IL-23 (red) or IL-12 (blue) for 24 h. Cytokine secretion in the supernatants was measured using Luminex technology ( n = 9). (B) Heatmap of measured cytokines. Dendograms on the top and left sides correspond to hierarchical clustering. (C) Boxplots (lines correspond to the first quartile, the median and the third quartile) representing the concentration of the indicated cytokines (adjusted p values, paired Wilcoxon test, Benjamini-Hochberg correction). (D) Single cell <t>secretome</t> of MAIT cells activated for 6 days with Tet in the presence or absence of IL-23 or IL-12 was assessed using Isolight technology. The heatmap represents the single-cell co-secretion patterns and their frequencies ( n = 4). The values for granzyme B are ∼15% for the Tet+IL-23 condition, and ∼17% for Tet+IL-12. See also <xref ref-type=Figure S1 and Tables S1 and . " width="250" height="auto" />
    Single Cell Secretome Human Inflammation Panel, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/single-cell+secretome+human+inflammation+panel/single+cell+secretome+human+inflammation+panel/pmc11850163-52-0-6
    Average 90 stars, based on 1 article reviews
    single-cell secretome human inflammation panel - by Bioz Stars, 2026-09
    90/100 stars

    Images

    1) Product Images from "IL-23 tunes inflammatory functions of human mucosal-associated invariant T cells"

    Article Title: IL-23 tunes inflammatory functions of human mucosal-associated invariant T cells

    Journal: iScience

    doi: 10.1016/j.isci.2025.111898

    IL-23 enhances production of cytotoxic molecules and IL-10 by MAIT cells (A) Percentage of IL-23R positive cells in different immune cell populations was assessed by flow cytometry on freshly isolated PBMCs ( n = 11). (B and C) PBMC were activated with Tet for 6 days or left unstimulated (black). Sorted MAIT cells (CD3 + CD161 + Va7.2 + ) were re-stimulated with Tet in the absence (gray) or presence of IL-23 (red) or IL-12 (blue) for 24 h. Cytokine secretion in the supernatants was measured using Luminex technology ( n = 9). (B) Heatmap of measured cytokines. Dendograms on the top and left sides correspond to hierarchical clustering. (C) Boxplots (lines correspond to the first quartile, the median and the third quartile) representing the concentration of the indicated cytokines (adjusted p values, paired Wilcoxon test, Benjamini-Hochberg correction). (D) Single cell secretome of MAIT cells activated for 6 days with Tet in the presence or absence of IL-23 or IL-12 was assessed using Isolight technology. The heatmap represents the single-cell co-secretion patterns and their frequencies ( n = 4). The values for granzyme B are ∼15% for the Tet+IL-23 condition, and ∼17% for Tet+IL-12. See also <xref ref-type=Figure S1 and Tables S1 and . " title="... paired Wilcoxon test, Benjamini-Hochberg correction). (D) Single cell secretome of MAIT cells activated for 6 days with ..." property="contentUrl" width="100%" height="100%"/>
    Figure Legend Snippet: IL-23 enhances production of cytotoxic molecules and IL-10 by MAIT cells (A) Percentage of IL-23R positive cells in different immune cell populations was assessed by flow cytometry on freshly isolated PBMCs ( n = 11). (B and C) PBMC were activated with Tet for 6 days or left unstimulated (black). Sorted MAIT cells (CD3 + CD161 + Va7.2 + ) were re-stimulated with Tet in the absence (gray) or presence of IL-23 (red) or IL-12 (blue) for 24 h. Cytokine secretion in the supernatants was measured using Luminex technology ( n = 9). (B) Heatmap of measured cytokines. Dendograms on the top and left sides correspond to hierarchical clustering. (C) Boxplots (lines correspond to the first quartile, the median and the third quartile) representing the concentration of the indicated cytokines (adjusted p values, paired Wilcoxon test, Benjamini-Hochberg correction). (D) Single cell secretome of MAIT cells activated for 6 days with Tet in the presence or absence of IL-23 or IL-12 was assessed using Isolight technology. The heatmap represents the single-cell co-secretion patterns and their frequencies ( n = 4). The values for granzyme B are ∼15% for the Tet+IL-23 condition, and ∼17% for Tet+IL-12. See also Figure S1 and Tables S1 and .

    Techniques Used: Flow Cytometry, Isolation, Luminex, Concentration Assay


    Figure Legend Snippet:

    Techniques Used: Control, Recombinant, CRISPR, Negative Control, Software

    Related Articles

    Flow Cytometry:

    Article Title: IL-23 tunes inflammatory functions of human mucosal-associated invariant T cells
    Article Snippet: Single-Cell Secretome Human Inflammation Panel , Bruker , Cat#1003-8.

    Isolation:

    Article Title: IL-23 tunes inflammatory functions of human mucosal-associated invariant T cells
    Article Snippet: Single-Cell Secretome Human Inflammation Panel , Bruker , Cat#1003-8.

    Luminex:

    Article Title: IL-23 tunes inflammatory functions of human mucosal-associated invariant T cells
    Article Snippet: Single-Cell Secretome Human Inflammation Panel , Bruker , Cat#1003-8.

    Concentration Assay:

    Article Title: IL-23 tunes inflammatory functions of human mucosal-associated invariant T cells
    Article Snippet: Single-Cell Secretome Human Inflammation Panel , Bruker , Cat#1003-8.

    Control:

    Article Title: IL-23 tunes inflammatory functions of human mucosal-associated invariant T cells
    Article Snippet: Single-Cell Secretome Human Inflammation Panel , Bruker , Cat#1003-8.

    Recombinant:

    Article Title: IL-23 tunes inflammatory functions of human mucosal-associated invariant T cells
    Article Snippet: Single-Cell Secretome Human Inflammation Panel , Bruker , Cat#1003-8.

    CRISPR:

    Article Title: IL-23 tunes inflammatory functions of human mucosal-associated invariant T cells
    Article Snippet: Single-Cell Secretome Human Inflammation Panel , Bruker , Cat#1003-8.

    Negative Control:

    Article Title: IL-23 tunes inflammatory functions of human mucosal-associated invariant T cells
    Article Snippet: Single-Cell Secretome Human Inflammation Panel , Bruker , Cat#1003-8.

    Software:

    Article Title: IL-23 tunes inflammatory functions of human mucosal-associated invariant T cells
    Article Snippet: Single-Cell Secretome Human Inflammation Panel , Bruker , Cat#1003-8.



    Similar Products

    single-cell secretome human inflammation panel  (Bruker Corporation)
    90
    Bruker Corporation single-cell secretome human inflammation panel
    IL-23 enhances production of cytotoxic molecules and IL-10 by MAIT cells (A) Percentage of IL-23R positive cells in different immune cell populations was assessed by flow cytometry on freshly isolated PBMCs ( n = 11). (B and C) PBMC were activated with Tet for 6 days or left unstimulated (black). Sorted MAIT cells (CD3 + CD161 + Va7.2 + ) were re-stimulated with Tet in the absence (gray) or presence of IL-23 (red) or IL-12 (blue) for 24 h. Cytokine secretion in the supernatants was measured using Luminex technology ( n = 9). (B) Heatmap of measured cytokines. Dendograms on the top and left sides correspond to hierarchical clustering. (C) Boxplots (lines correspond to the first quartile, the median and the third quartile) representing the concentration of the indicated cytokines (adjusted p values, paired Wilcoxon test, Benjamini-Hochberg correction). (D) Single cell <t>secretome</t> of MAIT cells activated for 6 days with Tet in the presence or absence of IL-23 or IL-12 was assessed using Isolight technology. The heatmap represents the single-cell co-secretion patterns and their frequencies ( n = 4). The values for granzyme B are ∼15% for the Tet+IL-23 condition, and ∼17% for Tet+IL-12. See also <xref ref-type=Figure S1 and Tables S1 and . " width="250" height="auto" />
    Single Cell Secretome Human Inflammation Panel, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/single-cell+secretome+human+inflammation+panel/single+cell+secretome+human+inflammation+panel/pmc11850163-52-0-6
    Average 90 stars, based on 1 article reviews
    single-cell secretome human inflammation panel - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    IL-23 enhances production of cytotoxic molecules and IL-10 by MAIT cells (A) Percentage of IL-23R positive cells in different immune cell populations was assessed by flow cytometry on freshly isolated PBMCs ( n = 11). (B and C) PBMC were activated with Tet for 6 days or left unstimulated (black). Sorted MAIT cells (CD3 + CD161 + Va7.2 + ) were re-stimulated with Tet in the absence (gray) or presence of IL-23 (red) or IL-12 (blue) for 24 h. Cytokine secretion in the supernatants was measured using Luminex technology ( n = 9). (B) Heatmap of measured cytokines. Dendograms on the top and left sides correspond to hierarchical clustering. (C) Boxplots (lines correspond to the first quartile, the median and the third quartile) representing the concentration of the indicated cytokines (adjusted p values, paired Wilcoxon test, Benjamini-Hochberg correction). (D) Single cell secretome of MAIT cells activated for 6 days with Tet in the presence or absence of IL-23 or IL-12 was assessed using Isolight technology. The heatmap represents the single-cell co-secretion patterns and their frequencies ( n = 4). The values for granzyme B are ∼15% for the Tet+IL-23 condition, and ∼17% for Tet+IL-12. See also <xref ref-type=Figure S1 and Tables S1 and . " width="100%" height="100%">

    Journal: iScience

    Article Title: IL-23 tunes inflammatory functions of human mucosal-associated invariant T cells

    doi: 10.1016/j.isci.2025.111898

    Figure Lengend Snippet: IL-23 enhances production of cytotoxic molecules and IL-10 by MAIT cells (A) Percentage of IL-23R positive cells in different immune cell populations was assessed by flow cytometry on freshly isolated PBMCs ( n = 11). (B and C) PBMC were activated with Tet for 6 days or left unstimulated (black). Sorted MAIT cells (CD3 + CD161 + Va7.2 + ) were re-stimulated with Tet in the absence (gray) or presence of IL-23 (red) or IL-12 (blue) for 24 h. Cytokine secretion in the supernatants was measured using Luminex technology ( n = 9). (B) Heatmap of measured cytokines. Dendograms on the top and left sides correspond to hierarchical clustering. (C) Boxplots (lines correspond to the first quartile, the median and the third quartile) representing the concentration of the indicated cytokines (adjusted p values, paired Wilcoxon test, Benjamini-Hochberg correction). (D) Single cell secretome of MAIT cells activated for 6 days with Tet in the presence or absence of IL-23 or IL-12 was assessed using Isolight technology. The heatmap represents the single-cell co-secretion patterns and their frequencies ( n = 4). The values for granzyme B are ∼15% for the Tet+IL-23 condition, and ∼17% for Tet+IL-12. See also Figure S1 and Tables S1 and .

    Article Snippet: Single-Cell Secretome Human Inflammation Panel , Bruker , Cat#1003-8.

    Techniques: Flow Cytometry, Isolation, Luminex, Concentration Assay

    Journal: iScience

    Article Title: IL-23 tunes inflammatory functions of human mucosal-associated invariant T cells

    doi: 10.1016/j.isci.2025.111898

    Figure Lengend Snippet:

    Article Snippet: Single-Cell Secretome Human Inflammation Panel , Bruker , Cat#1003-8.

    Techniques: Control, Recombinant, CRISPR, Negative Control, Software